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Article

The C242T polymorphism of the p22-phox gene (CYBA) is associated with higher left ventricular mass in Brazilian hypertensive patients.

BMC medical genetics - 31 Aug 2011

Schreiber Roberto, Ferreira-Sae Maria C, Ronchi Juliana A, Pio-Magalhães José A, Cipolli José A, Matos-Souza José R, Mill José G, Vercesi Aníbal E, Krieger José E, Franchini Kleber G, Pereira Alexandre C, Nadruz Junior Wilson

Abstract excerpt

BACKGROUND: Reactive oxygen species have been implicated in the physiopathogenesis of hypertensive end-organ damage. This study investigated the impact of the C242T polymorphism of the p22-phox gene (CYBA) on left ventricular structure in Brazilian hypertensive subjects. METHODS: We cross-sectionally evaluated 561 patients from 2 independent centers [Campinas (n = 441) and Vitória (n = 120)] by clinical history,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21884584
DOI: 10.1186/1471-2350-12-114
PMCID: PMC3182137

Genes

CYBA

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