Article
Association between p22PHOX gene C242T polymorphism and hypertension in end-stage kidney disease patients.
Journal of human hypertension - 1 Jan 2021
Buraczynska Monika, Drop Bartlomiej, Jacob Jerry, Zaluska Wojciech
Abstract excerpt
Oxidative stress plays an important role in hypertension associated vascular damage. It is mediated by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation. The C242T polymorphism in the p22PHOX gene encoding essential subunit of NADPH oxidase was associated with CVD, hypertension, and endothelial function. The aim of this study was to assess a potential association of C242T polymorphism with...
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