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Article

Association between the C242T polymorphism in the p22phox gene with arterial stiffness in the Brazilian population.

Physiological genomics - 1 May 2012

de Oliveira Alvim Rafael, Santos Paulo Caleb Junior Lima, Dias Rodrigo Gonçalves, Rodrigues Mariliza Velho, de Sa Cunha Roberto, Mill José Geraldo, Junior Wilson Nadruz, Krieger José Eduardo, Pereira Alexandre Costa

Abstract excerpt

NADPH oxidase p22phox subunit is responsible for the production of reactive oxygen species in the vascular tissue. The C242T polymorphism in the p22phox gene has been associated with diverse coronary artery disease phenotypes, but the findings about the protective or harmful effects of the T allele are still controversial. Our main aim was to assess the effect of p22phox C242T genotypes on arterial stiffness, a...

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PMID: 22496489
DOI: 10.1152/physiolgenomics.00122.2011

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TNF

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Association between the C242T polymorphism in the p22phox gene with arterial stiffness in the Brazilian population.PMID 22496489Read ↗

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The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension.Semantic proximity Read ↗

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The effect of p22(phox) -930A/G, A640G and C242T polymorphisms of NADPH oxidase on peripheral and central pressures in healthy, normotensive individuals.Semantic proximity Read ↗

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