vac2: a yeast mutant which distinguishes vacuole segregation from Golgi-to-vacuole protein targeting.

doi:10.1002/j.1460-2075.1991.tb07698.x

Back to search

Article

vac2: a yeast mutant which distinguishes vacuole segregation from Golgi-to-vacuole protein targeting.

The EMBO journal - 1 Jul 1991

Shaw J M, Wickner W T

Abstract excerpt

We have isolated four yeast mutants that are unable to partition maternal vacuoles into growing buds. Three of these vacuole segregation (vac) mutants also mislocalize the vacuolar protease carboxypeptidase Y (CPY) to the cell surface, a phenotype previously reported for vac strains. A fourth mut...

Topics

Aspartic Acid Endopeptidases
Biological Transport
Carboxypeptidases
Cathepsin A
Cell Nucleus
Fungal Proteins
Golgi Apparatus
Kinetics
Mitochondria
Mutation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Temperature
Vacuoles

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.