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Article

Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway.

The Journal of cell biology - 1 Nov 1995

Harding T M, Morano K A, Scott S V, Klionsky D J

Abstract excerpt

In Saccharomyces cerevisiae the vacuolar protein aminopeptidase I (API) is localized to the vacuole independent of the secretory pathway. The alternate targeting mechanism used by this protein has not been characterized. API is synthesized as a 61-kD soluble cytosolic precursor. Upon delivery to...

Topics

Alleles
Aminopeptidases
Cytoplasm
Genetic Testing
Hydrogen-Ion Concentration
Kinetics
Mutation
Phenotype
Protein Precursors
Protein Processing, Post-Translational
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vacuoles

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Identifiers

PMID: 7593182
DOI: 10.1083/jcb.131.3.591
PMCID: PMC2120622

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7593182-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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