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Article

Mutants of Saccharomyces cerevisiae that block intervacuole vesicular traffic and vacuole division and segregation.

Proceedings of the National Academy of Sciences of the United States of America - 1 Feb 1990

Weisman L S, Emr S D, Wickner W T

Abstract excerpt

Intervacuole vesicular exchange and the segregation of parental vacuole material into the bud are strikingly impaired in a temperature-sensitive yeast mutant, vac1-1. At the nonpermissive temperature, haploid vac1-1 cells show a pronounced delay in separation of mature buds from the mother cell and accumulate cells with multiple buds. At both the permissive and restrictive temperatures, daughter cells are...

Topics

Cell Nucleus
Dextrans
Fluorescein-5-isothiocyanate
Fluoresceins
Fluorescent Dyes
Mitochondria
Mutation
Saccharomyces cerevisiae
Vacuoles

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1689059
DOI: 10.1073/pnas.87.3.1076
PMCID: PMC53413

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1689059-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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