Article
Plasma membrane localization of the Yck2p yeast casein kinase 1 isoform requires the C-terminal extension and secretory pathway function.
Journal of cell science - 15 Dec 2002
Babu Praveen, Bryan Joshua D, Panek Heather R, Jordan Solomon L, Forbrich Brynn M, Kelley Shannon C, Colvin Richard T, Robinson Lucy C
Abstract excerpt
The S. cerevisiae Yck2 protein is a plasma membrane-associated member of the casein kinase 1 protein kinase family that, with its homolog Yck1p, is required for bud morphogenesis, cytokinesis, endocytosis and other cellular processes. Membrane localization of Yckp is critical for its function, since soluble mutants do not provide sufficient biological activity to sustain normal growth. Yck2p has neither a...
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