Article
Involvement of long chain fatty acid elongation in the trafficking of secretory vesicles in yeast.
The Journal of cell biology - 30 Nov 1998
David D, Sundarababu S, Gerst J E
Abstract excerpt
Members of the synaptobrevin/VAMP family of v-SNAREs are thought to be essential for vesicle docking and exocytosis in both lower and higher eukaryotes. Here, we describe yeast mutants that appear to bypass the known v-SNARE requirement in secretion. Recessive mutations in either VBM1 or VBM2, wh...
Topics
- Alleles
- Biological Transport, Active
- Carboxypeptidases
- Cathepsin A
- Ceramides
- Cloning, Molecular
- Endoplasmic Reticulum
- Exocytosis
- Fatty Acids
- Fungal Proteins
- Gene Deletion
- Genes, Fungal
- Glycoside Hydrolases
- Membrane Glycoproteins
- Membrane Proteins
- Microscopy, Electron
- Molecular Sequence Data
- Mutation