Article
The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae.
European journal of cell biology - 1 Aug 1996
Chen Y J, Stevens T H
Abstract excerpt
To better understand the process of protein sorting to the yeast vacuole, the VPS8 gene was identified and characterized. VPS8 encodes a membrane-associated hydrophilic protein of 135 kDa (Vps8p), which is required for the accurate sorting of the vacuolar hydrolase, carboxypeptidase Y (CPY). vps8...
Topics
- Amino Acid Sequence
- Carrier Proteins
- Cloning, Molecular
- Fluorescent Antibody Technique, Indirect
- Fungal Proteins
- Genes, Fungal
- Golgi Apparatus
- Immunoblotting
- Molecular Sequence Data
- Mutation
- Plasmids
- Receptors, Cell Surface
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Vacuoles
- Vesicular Transport Proteins