Article
Modulation of Nicotine but Not Ethanol Preference by the Mouse Chrna4 A529T Polymorphism.
1 Jan 2005
Abstract excerpt
Available evidence indicates that common genes influence alcohol and tobacco abuse in humans. The studies reported here used mouse models to evaluate the hypothesis that genetically determined variability in the alpha4beta2* nicotinic receptor modulates genetically determined variability in the intake of both nicotine and alcohol. Data obtained with inbred mouse strains suggested an association between a...
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