Article
SMC1B is present in mammalian somatic cells and interacts with mitotic cohesin proteins.
Scientific reports - 17 Dec 2015
Mannini Linda, Cucco Francesco, Quarantotti Valentina, Amato Clelia, Tinti Mara, Tana Luigi, Frattini Annalisa, Delia Domenico, Krantz Ian D, Jessberger Rolf, Musio Antonio
Abstract excerpt
Cohesin is an evolutionarily conserved protein complex that plays a role in many biological processes: it ensures faithful chromosome segregation, regulates gene expression and preserves genome stability. In mammalian cells, the mitotic cohesin complex consists of two structural maintenance of chromosome proteins, SMC1A and SMC3, the kleisin protein RAD21 and a fourth subunit either STAG1 or STAG2. Meiotic...
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