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Article

Methods for analyzing checkpoint responses in Caenorhabditis elegans.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2004

Gartner Anton, MacQueen Amy J, Villeneuve Anne M

Abstract excerpt

In response to genotoxic insults, cells activate DNA damage checkpoint pathways that stimulate DNA repair, lead to a transient cell cycle arrest, and/or elicit programmed cell death (apoptosis) of affected cells. The Caenorhabditis elegans germ line was recently established as a model system to study these processes in a genetically tractable, multicellular organism. The utility of this system was revealed by the...

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PMID: 15187259
DOI: 10.1385/1-59259-788-2:257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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