Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic intracellular distribution of Notch during activation and asymmetric cell division revealed by functional fluorescent fusion proteins.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Jun 2010

Kawahashi Koji, Hayashi Shigeo

Abstract excerpt

Notch signaling mediates intercellular communication required for cell fate specification. Because the majority of Notch proteins exist as an intracellular pool, information on intracellular trafficking of Notch is essential for understanding its regulation. To observe trafficking of Notch protein in vivo, we constructed a Notch protein with green fluorescent protein (GFP) inserted into the intracellular domain....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila

Share to Drosophila Proteins

Share to Green Fluorescent Proteins

Share to Phenotype

Share to Receptors, Notch

Share to Signal Transduction

Source

Identifiers

PMID: 20482700
DOI: 10.1111/j.1365-2443.2010.01412.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic intracellular distribution of Notch during activation and asymmetric cell division revealed by functional fluorescent fusion proteins.PMID 20482700Read ↗

Endosomal entry regulates Notch receptor activation in Drosophila melanogaster.Semantic proximity Read ↗

Genetic identification of intracellular trafficking regulators involved in Notch-dependent binary cell fate acquisition following asymmetric cell division.Semantic proximity Read ↗

Imaging clathrin dynamics in Drosophila melanogaster hemocytes reveals a role for actin in vesicle fission.Semantic proximity Read ↗

Notch signaling during development requires the function of awd, the Drosophila homolog of human metastasis suppressor gene Nm23.Semantic proximity Read ↗

Activation of Notch in lgd mutant cells requires the fusion of late endosomes with the lysosome.Semantic proximity Read ↗

The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor.Semantic proximity Read ↗

Nuclear access and action of notch in vivo.Semantic proximity Read ↗

Drosophila liquid facets-Related encodes Golgi epsin and is an essential gene required for cell proliferation, growth, and patterning.Semantic proximity Read ↗

Ca(2+)-ATPase function is required for intracellular trafficking of the Notch receptor in Drosophila.Semantic proximity Read ↗

Auxilin is essential for Delta signaling.Semantic proximity Read ↗

Endocytic internalization routes required for delta/notch signaling.Semantic proximity Read ↗

Dynamic features of adherens junctions during Drosophila embryonic epithelial morphogenesis revealed by a Dalpha-catenin-GFP fusion protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.