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Article

Nullity of GSTT1/GSTM1 related to pesticides is associated with Parkinson's disease.

Arquivos de neuro-psiquiatria - 1 Aug 2013

Pinhel Marcela Augusta de Souza, Sado Caroline Leiko, Longo Gabriela Dos Santos, Gregório Michele Lima, Amorim Gisele Sousa, Florim Greiciane Maria da Silva, Mazeti Camila Montoro, Martins Denise Poltronieri, Oliveira Fábio de Nazaré, Nakazone Marcelo Arruda, Tognola Waldir Antonio, Souza Dorotéia Rossi Silva

Abstract excerpt

Genetic and environmental factors affect the pathogenesis of Parkinson's disease (PD). Genetic variants of the enzyme glutathione S-transferases (GST) may be related to the disease. This study aimed to evaluate the influence of genetic variants of GST (GSTT1/GSTM1) and their association with the exposure to environmental toxins in PD patients. We studied 254 patients with PD and 169 controls. The GSTM1/GSTT1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23982010
DOI: 10.1590/0004-282X20130076

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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