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Article

The interplay between environmental and genetic factors in Parkinson's disease susceptibility: the evidence for pesticides.

Toxicology - 10 May 2013

Dardiotis Efthimios, Xiromerisiou Georgia, Hadjichristodoulou Christos, Tsatsakis Aristidis M, Wilks Martin F, Hadjigeorgiou Georgios M

Abstract excerpt

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by dopaminergic neuron loss in the substantia nigra. Several genetic and environmental factors have been implicated in the pathogenesis of PD. Single risk factors are likely to exert relatively minor effects, whereas their interaction may prove to be sufficient to cause PD. In the present review we summarize current knowledge from human...

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Identifiers

PMID: 23295711
DOI: 10.1016/j.tox.2012.12.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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