Article
The influence of CTLA-4 gene polymorphism on long-term kidney allograft function in Caucasian recipients.
Transplant immunology - 1 Jul 2010
Kusztal Mariusz, Kościelska-Kasprzak Katarzyna, Drulis-Fajdasz Dominika, Magott-Procelewska Maria, Patrzałek Dariusz, Janczak Dariusz, Chudoba Paweł, Klinger Marian
Abstract excerpt
The aim of the study was to examine whether CTLA-4 (CD152) and CD28 gene polymorphisms affect the outcome of kidney transplantation (KTx). Polymorphisms of the CTLA-4 gene (-318 C>T, +49 A>G, and the microsatellite polymorphism in the 3'UTR of exon 4 (AT)(n)) and a CD28 gene (IVS3 +17T>C) were investigated in 314 allograft recipients with a mean age of 41.9+/-12 years. The median time since KTx was 97.5 months....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.