Association between IVS3 +17T/C CD28 gene polymorphism and the acute kidney allograft rejection.

doi:10.1016/j.trim.2013.12.002

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Article

Association between IVS3 +17T/C CD28 gene polymorphism and the acute kidney allograft rejection.

Transplant immunology - 1 Mar 2014

Pawlik Andrzej, Dabrowska-Zamojcin Ewa, Dziedziejko Violetta, Safranow Krzysztof, Domanski Leszek

Abstract excerpt

CD28 is a costimulatory molecule which plays an important role in T cell-mediated immune response and transplantation. The aim of the present study was to examine the association between the IVS3 +17T/C (rs3116496:T/C) polymorphism in the CD28 gene and the development of delayed renal graft function (DGF), as well as the acute rejection and chronic allograft nephropathy. A total of 270 recipients of the first...

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PMID: 24368148
DOI: 10.1016/j.trim.2013.12.002

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