Article
Ctla-4 exon 1 (+49) and promoter (-318) gene polymorphisms in kidney transplantation.
Transplantation proceedings - 1 Sept 2006
Gorgi Y, Sfar I, Abdallah T Ben, Abderrahim E, Ayed S Jendoubi, Aouadi H, Bardi R, Ayed K
Abstract excerpt
To investigate the association between kidney transplant rejection and the polymorphisms of CTLA-4 gene exon 1(+49) and promoter (-318), genomic DNA of 70 renal transplant recipients and 110 healthy blood donors were genotyped by PCR-RFLP and PCR-SSP, respectively. The patients were classified in two groups: G1 included 33 HLA-identical recipients and G2, 37 one haplo-identical recipients. Thirty-one recipients...
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