Article
Impact of HLA-G 14-bp polymorphism on acute rejection and cytomegalovirus infection in kidney transplant recipients from northwestern China.
Transplant immunology - 1 Oct 2012
Jin Zhan-Kui, Xu Cui-Xiang, Tian Pu-Xun, Xue Wu-Jun, Ding Xiao-Ming, Zheng Jin, Ding Chen-Guang, Ge Guan-Qun, Mao Tian-Ci, Lin Yuan
Abstract excerpt
Human leukocyte antigen (HLA)-G plays an important role in promoting transplant tolerance and helping human cytomegalovirus (CMV) to subvert host defenses. Strong evidence suggests that HLA-G 14-bp insertion/deletion polymorphism influences the stability of HLA-G mRNAs and levels of protein expression. We hypothesized that HLA-G 14-bp polymorphism of recipients has an influence on the risk of acute rejection (AR)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
