Article
Evidence for association of the non-duplicated region of CHRNA7 gene with bipolar disorder but not with Schizophrenia.
Psychiatric genetics - 1 Dec 2010
Ancín Inés, Barabash Ana, Vázquez-Álvarez Blanca, Santos José Luis, Sánchez-Morla Eva, Martínez José Luis, Aparicio Ana, Peláez José Carlos, Díaz José Antonio Cabranes
Abstract excerpt
OBJECTIVE: Biological evidence in both human and animal studies suggests α7 neuronal nicotinic acetylcholine receptor subunit gene (CHRNA7) as a suitable functional candidate for genetic studies in psychiatric populations. This gene maps to chromosome 15q13-14, a major linkage hotspot for schizophrenia (SCH) and bipolar disorder (BD). In this study we examine the role of CHRNA7 in influencing the risk of SCH and...
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