Article
Population-based and family-based association studies of an (AC)n dinucleotide repeat in alpha-7 nicotinic receptor subunit gene and schizophrenia.
Schizophrenia research - 1 Jun 2006
Fan Jin-Bo, Ma Jie, Li Xing-Wang, Zhang Chang-Shun, Sun Wei-Wei, He Guang, Gu Niu-Fan, Feng Guo-Yin, St Clair David, He Lin
Abstract excerpt
The human alpha-7 neuronal nicotinic receptor subunit (CHRNA7) gene, located at chromosome 15q13.2, represents a strong candidate gene for schizophrenia. We have examined an (AC)n dinucleotide repeat in intron 2 of the CHRNA7 gene, which was previously shown to be strongly linked with schizophrenia, using both population-based and family-based association studies. In the population-based study, no significant...
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