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Article

Linkage disequilibrium analysis of the CHRNA7 gene and its partially duplicated region in schizophrenia.

Neuroscience research - 1 Feb 2007

Iwata Yasuhide, Nakajima Mizuho, Yamada Kazuo, Nakamura Kazuhiko, Sekine Yoshimoto, Tsuchiya Kenji J, Sugihara Genichi, Matsuzaki Hideo, Suda Shiro, Suzuki Katsuaki, Takei Nori, Mori Norio, Iwayama Yoshimi, Takao Hitomi, Yoshikawa Takeo, Riley Brien, Makoff Andrew, Sham Pak, Chen Ronald, Collier David

Abstract excerpt

Several previous studies have reported a significant linkage between markers in the alpha 7 nicotinic cholinergic receptor subunit (CHRNA7) gene and either schizophrenia or the P50 sensory gating deficit, a schizophrenia endophenotype. However, CHRFAM7A, a partially duplicated gene 1.6Mb upstream...

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Source

Identifiers

PMID: 17113175
DOI: 10.1016/j.neures.2006.10.002

Genes

CHRNA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17113175-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Linkage disequilibrium analysis of the CHRNA7 gene and its partially duplicated region in schizophrenia.PMID 17113175Read ↗

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The -2 bp deletion in exon 6 of the 'alpha 7-like' nicotinic receptor subunit gene is a risk factor for the P50 sensory gating deficit.Semantic proximity Read ↗

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