Unanswered questions in the regulation and function of the duplicated α7 nicotinic receptor gene CHRFAM7A.

Abstract excerpt

The α7 nicotinic receptor (α7 nAChR) is an important entry point for Ca2+ into the cell, which has broad and important effects on gene expression and function. The gene (CHRNA7), mapping to chromosome (15q14), has been genetically linked to a large number of diseases, many of which involve defects in cognition. While numerous mutations in CHRNA7 are associated with mental illness and inflammation, an important...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to alpha7 Nicotinic Acetylcholine Receptor
• Share to Cognition
• Share to DNA Copy Number Variations