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Article

The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function.

Neuropharmacology - 1 Sept 2015

Sinkus Melissa L, Graw Sharon, Freedman Robert, Ross Randal G, Lester Henry A, Leonard Sherry

Abstract excerpt

The human α7 neuronal nicotinic acetylcholine receptor gene (CHRNA7) is ubiquitously expressed in both the central nervous system and in the periphery. CHRNA7 is genetically linked to multiple disorders with cognitive deficits, including schizophrenia, bipolar disorder, ADHD, epilepsy, Alzheimer's disease, and Rett syndrome. The regulation of CHRNA7 is complex; more than a dozen mechanisms are known, one of which...

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Identifiers

PMID: 25701707
DOI: 10.1016/j.neuropharm.2015.02.006
PMCID: PMC4486515

Genes

CHRNA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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