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Article

A powerful score test to detect positive selection in genome-wide scans.

European journal of human genetics : EJHG - 1 Oct 2010

Zhong Ming, Lange Kenneth, Papp Jeanette C, Fan Ruzong

Abstract excerpt

One of the surest signatures of recent positive selection is a local elevation of advantageous allele frequency and linkage disequilibrium (LD). We proposed to detect such hitchhiking effects by using extended stretches of homozygosity as a surrogate indicator of recent positive selection. An extended haplotype-based homozygosity score test (EHHST) was developed to detect excess homozygosity. The EHHST...

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Identifiers

PMID: 20461112
DOI: 10.1038/ejhg.2010.60
PMCID: PMC2987455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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