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Article

Exploring the occurrence of classic selective sweeps in humans using whole-genome sequencing data sets.

Molecular biology and evolution - 1 Jul 2014

Fagny Maud, Patin Etienne, Enard David, Barreiro Luis B, Quintana-Murci Lluis, Laval Guillaume

Abstract excerpt

Genome-wide scans for selection have identified multiple regions of the human genome as being targeted by positive selection. However, only a small proportion has been replicated across studies, and the prevalence of positive selection as a mechanism of adaptive change in humans remains controversial. Here we explore the power of two haplotype-based statistics--the integrated haplotype score (iHS) and the Derived...

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PMID: 24694833
DOI: 10.1093/molbev/msu118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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