Article
A practical genome scan for population-specific strong selective sweeps that have reached fixation.
PloS one - 14 Mar 2007
Kimura Ryosuke, Fujimoto Akihiro, Tokunaga Katsushi, Ohashi Jun
Abstract excerpt
Phenotypic divergences between modern human populations have developed as a result of genetic adaptation to local environments over the past 100,000 years. To identify genes involved in population-specific phenotypes, it is necessary to detect signatures of recent positive selection in the human genome. Although detection of elongated linkage disequilibrium (LD) has been a powerful tool in the field of...
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