Article
Inhibitor of DNA binding 4 (ID4) regulation of adipocyte differentiation and adipose tissue formation in mice.
The Journal of biological chemistry - 30 Jul 2010
Murad Joana M, Place Chelsea S, Ran Cong, Hekmatyar Shahryar K N, Watson Nathan P, Kauppinen Risto A, Israel Mark A
Abstract excerpt
Inhibitor of DNA binding 4 (ID4) is a helix-loop-helix protein that heterodimerizes with basic helix-loop-helix transcription factors inhibiting their function. ID4 expression is important for adipogenic differentiation of the 3T3-L1 cell line, and inhibition of ID4 is associated with a concomitant decrease in CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma mRNA and...
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