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Article

Role of Id family proteins in growth control

5 Dec 2001

Abstract excerpt

Id proteins (inhibitors of DNA binding/differentiation) are negative regulators of basic helix-loop-helix (bHLH) type transcription factors, which promote the differentiation of various cell types. In addition to their "classical" ability to inhibit cell differentiation, they are able to stimulate cell cycle progression. These facts suggest that Id proteins play a role in keeping precursor cells immature and in...

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PMID: 11807807
DOI: 10.1002/jcp.10042

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