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Article

Vestigial-like 3 is an inhibitor of adipocyte differentiation

15 Nov 2012

Abstract excerpt

Adipose differentiation is a complex process controlled by a network of transcription factors and co-regulators. We compared the global gene expression patterns of adipogenic and nonadipogenic clones of 3T3-F442A preadipocytes and identified the transcriptional cofactor, vestigial-like 3 (Vgll3), as an inhibitor of adipogenesis. Vgll3 expression is down-regulated during terminal adipocyte differentiation in vitro...

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PMID: 23152581
DOI: 10.1194/jlr.m032755

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