Article
Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study.
Journal of lipid research - 1 Nov 2004
Lai Chao-Qiang, Demissie Serkalem, Cupples L Adrienne, Zhu Yueping, Adiconis Xian, Parnell Laurence D, Corella Dolores, Ordovas Jose M
Abstract excerpt
Several polymorphisms in the APOA5 gene have been associated with increased plasma triglyceride (TG) concentrations. However, associations between APOA5 and lipoprotein subclasses, remnant-like particles (RLPs), and cardiovascular disease (CVD) risk have been less explored. We investigated associations of five APOA5 single-nucleotide polymorphisms (SNPs; -1131T>C, -3A>G, 56C>G IVS3+ 476G>A, and 1259T>C) with...
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