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Article

A promoter variant of the APOA5 gene increases atherogenic LDL levels and arterial stiffness in hypertriglyceridemic patients.

PloS one - 1 Jan 2017

Kim Minjoo, Kim Minkyung, Yoo Hye Jin, Lee Eunji, Chae Jey Sook, Lee Sang-Hyun, Lee Jong Ho

Abstract excerpt

Hypertriglyceridemia is recognized as an independent risk factor for coronary artery disease. The apolipoprotein A5 gene (APOA5) is a key regulator of triglyceride levels. We aimed to evaluate the associations of single nucleotide polymorphisms (SNPs) in APOA5, including -1131T>C and c.553G>T, with hypertriglyceridemia, apoA5 concentrations, atherogenic LDL cholesterol levels, and arterial stiffness in...

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Share to Apolipoprotein A-V
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Atherosclerosis

Share to Cholesterol, LDL

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Share to Malondialdehyde

Share to Promoter Regions, Genetic

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Source

Open in PubMed Open full text

Identifiers

PMID: 29211729
DOI: 10.1371/journal.pone.0186693
PMCID: PMC5718602

Genes

APOA5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A promoter variant of the APOA5 gene increases atherogenic LDL levels and arterial stiffness in hypertriglyceridemic patients.PMID 29211729Read ↗

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