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Article

Surprises From Genetic Analyses of Lipid Risk Factors for Atherosclerosis.

Circulation research - 19 Feb 2016

Musunuru Kiran, Kathiresan Sekar

Abstract excerpt

Observational epidemiological studies have associated plasma lipid concentrations with risk for coronary heart disease (CHD), but these studies cannot distinguish cause from mere correlation. Human genetic studies, when considered with the results of randomized controlled trials of medications, can potentially shed light on whether lipid biomarkers are causal for diseases. Genetic analyses and randomized trials...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26892959
DOI: 10.1161/CIRCRESAHA.115.306398
PMCID: PMC4762058

Genes

ANGPTL4
APOA5
APOC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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