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Article

Development of head organizer of the mouse embryo depends on a high level of mitochondrial metabolism.

Developmental biology - 1 Aug 2010

Zhou Xin, Anderson Kathryn V

Abstract excerpt

Mouse genetic studies have defined a set of signaling molecules and transcription factors that are necessary to induce the forebrain. Here we describe an ENU-induced mouse mutation, nearly headless (nehe), that was identified based on the specific absence of most of the forebrain at midgestation. Positional cloning and genetic analysis show that, unlike other mouse mutants that disrupt specification of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20450902
DOI: 10.1016/j.ydbio.2010.04.031
PMCID: PMC2909343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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