Article
The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure.
Development (Cambridge, England) - 1 Sept 2010
Mao Jinzhe, McKean David M, Warrier Sunita, Corbin Joshua G, Niswander Lee, Zohn Irene E
Abstract excerpt
Neural tube defects (NTDs) are some of the most common birth defects observed in humans. The incidence of NTDs can be reduced by peri-conceptional folic acid supplementation alone and reduced even further by supplementation with folic acid plus a multivitamin. Here, we present evidence that iron maybe an important nutrient necessary for normal development of the neural tube. Following implantation of the mouse...
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