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Article

AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes.

Genes & development - 1 Mar 2016

Young Nathan P, Kamireddy Anwesh, Van Nostrand Jeanine L, Eichner Lillian J, Shokhirev Maxim Nikolaievich, Dayn Yelena, Shaw Reuben J

Abstract excerpt

Faithful execution of developmental programs relies on the acquisition of unique cell identities from pluripotent progenitors, a process governed by combinatorial inputs from numerous signaling cascades that ultimately dictate lineage-specific transcriptional outputs. Despite growing evidence that metabolism is integrated with many molecular networks, how pathways that control energy homeostasis may affect cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26944679
DOI: 10.1101/gad.274142.115
PMCID: PMC4782048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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