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Article

Association between the methylenetetrahydrofolate reductase polymorphisms and risk of acute lymphoblastic leukemia in Serbian children.

Journal of pediatric hematology/oncology - 1 May 2010

Damnjanovic Tatjana, Milicevic Radomir, Novkovic Tanja, Jovicic Olivera, Bunjevacki Vera, Jekic Biljana, Lukovic Ljiljana, Novakovic Ivana, Redzic Danka, Milasin Jelena

Abstract excerpt

SUMMARY: Methylenetetrahydrofolate reductase (MTHFR) regulates the metabolism of folate and methionine, essential components of DNA synthesis and methylation. Polymorphisms in the MTHFR gene have been associated with susceptibility to some types of cancer. We investigated a possible association of MTHFR polymorphisms (677C>T and 1298A>C) and increased risk for acute lymphoblastic leukemia in 78 affected children....

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Source

Identifiers

PMID: 20445408
DOI: 10.1097/MPH.0b013e3181cbd252

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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