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Article

Assessment of the relationship between methylenetetrahydrofolate reductase polymorphism and acute lymphoblastic leukemia: Evidence from an updated meta-analysis.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners - 1 Oct 2020

Frikha Rim

Abstract excerpt

OBJECTIVE: The methylenetetrahydrofolate reductase gene C677T polymorphism is closely related to the acute lymphoblastic leukemia. Several case-control studies have investigated this association; however, no conclusions could be drawn. A comprehensive updated meta-analysis is established to explain these contradictions and clarify the overall impact of this variant on the susceptibility to acute lymphoblastic...

Topics

Adult
Asian People
Case-Control Studies
Child
Genetic Predisposition to Disease
Humans
Methylenetetrahydrofolate Reductase (NADPH2)
Polymorphism, Genetic
Precursor Cell Lymphoblastic Leukemia-Lymphoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32070201
DOI: 10.1177/1078155219900914

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