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Article

Association analysis of GRIN1 and GRIN2B polymorphisms and Parkinson's disease in a hospital-based case-control study.

Neuroscience letters - 5 Jul 2010

Wu Shey-Lin, Wang Wen-Fu, Shyu Hann-Yeh, Ho Ying-Jui, Shieh Jia-Ching, Fu Yi-Ping, Wu Shwu-Tzy, Cheng Chun-Wen

Abstract excerpt

Hyperactivation of N-methyl-d-aspartate receptors (NMDARs) leads to neuronal excitotoxicity and is suggested to play a role in many brain disorders, including Alzheimer's disease and schizophrenia. However, the association between polymorphisms in the genes that code for NMDAR subunits, N-methyl-d-aspartate 1 and 2B (GRIN1 and GRIN2B) and Parkinson's disease (PD) remains unclear. In a hospital-based case-control...

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Source

Identifiers

PMID: 20438806
DOI: 10.1016/j.neulet.2010.04.063

Genes

GRIN1

Variants

rs2301364
rs2301364

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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