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Article

Caffeine interaction with glutamate receptor gene GRIN2A: Parkinson's disease in Swedish population.

PloS one - 1 Jan 2014

Yamada-Fowler Naomi, Fredrikson Mats, Söderkvist Peter

Abstract excerpt

A complex interplay between genetic and environmental factors is thought to be involved in the etiology of Parkinson's disease (PD). A recent genome-wide association and interaction study (GWAIS) identified GRIN2A, which encodes an NMDA-glutamate-receptor subunit involved in brain's excitatory neurotransmission, as a PD genetic modifier in inverse association with caffeine intake. Here in, we attempted to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24915238
DOI: 10.1371/journal.pone.0099294
PMCID: PMC4051678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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