Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in FGF20 modulates hippocampal biology.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Apr 2010

Lemaitre Herve, Mattay Venkata S, Sambataro Fabio, Verchinski Beth, Straub Richard E, Callicott Joseph H, Kittappa Raja, Hyde Thomas M, Lipska Barbara K, Kleinman Joel E, McKay Ronald, Weinberger Daniel R

Abstract excerpt

We explored the effect of single-nucleotide polymorphisms (SNPs) in the fibroblast growth factor 20 gene (FGF20) associated with risk for Parkinson's disease on brain structure and function in a large sample of healthy young-adult human subjects and also in elderly subjects to look at the interaction between genetic variations and age (N = 237; 116 men; 18-87 years). We analyzed high-resolution anatomical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Cognition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factors

Share to Hippocampus

Share to MicroRNAs

Share to Organ Size

Share to Receptor, Fibroblast Growth Factor, Type 1

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 20427658
DOI: 10.1523/JNEUROSCI.5773-09.2010
PMCID: PMC2909689

Genes

FGF20
FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in FGF20 modulates hippocampal biology.PMID 20427658Read ↗

The interaction effects of age, APOE and common environmental risk factors on human brain structure.Semantic proximity Read ↗

Novel genetic loci associated with hippocampal volume.Semantic proximity Read ↗

Sex-Dependent Age Trajectories of Subcortical Brain Structures: Analysis of Large-Scale Percentile Models and Shape MorphometrySemantic proximity Read ↗

Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease.Semantic proximity Read ↗

Shared molecular genetic factors influence subcortical brain morphometry and Parkinson’s disease riskSemantic proximity Read ↗

Brain size links neurodevelopment to neurodegeneration in Parkinson's diseaseSemantic proximity Read ↗

Characterizing the role of brain derived neurotrophic factor genetic variation in Alzheimer's disease neurodegeneration.Semantic proximity Read ↗

Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease.Semantic proximity Read ↗

Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein.Semantic proximity Read ↗

Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.Semantic proximity Read ↗

Evaluation of FGF 20 variants for susceptibility to Parkinson's disease in Eastern Indians.Semantic proximity Read ↗

The association of RAB18 gene polymorphism (rs3765133) with cerebellar volume in healthy adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.