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Article

Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease.

BMC genomics - 3 Oct 2014

Ashbrook David G, Williams Robert W, Lu Lu, Stein Jason L, Hibar Derrek P, Nichols Thomas E, Medland Sarah E, Thompson Paul M, Hager Reinmar

Abstract excerpt

BACKGROUND: Variation in hippocampal volume has been linked to significant differences in memory, behavior, and cognition among individuals. To identify genetic variants underlying such differences and associated disease phenotypes, multinational consortia such as ENIGMA have used large magnetic resonance imaging (MRI) data sets in human GWAS studies. In addition, mapping studies in mouse model systems have...

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Identifiers

PMID: 25280473
DOI: 10.1186/1471-2164-15-850
PMCID: PMC4192369

Genes

MGST3

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Source receipt: pubmed, retrieved 7 Sept 2026.

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