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Article

Characterizing the role of brain derived neurotrophic factor genetic variation in Alzheimer's disease neurodegeneration.

PloS one - 1 Jan 2013

Honea Robyn A, Cruchaga Carlos, Perea Rodrigo D, Saykin Andrew J, Burns Jeffrey M, Weinberger Daniel R, Goate Alison M

Abstract excerpt

There is accumulating evidence that neurotrophins, like brain-derived neurotrophic factor (BDNF), may impact aging and Alzheimer's Disease. However, traditional genetic association studies have not found a clear relationship between BDNF and AD. Our goal was to test whether BDNF single nucleotide polymorphisms (SNPs) impact Alzheimer's Disease-related brain imaging and cognitive markers of disease. We completed...

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Source

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Identifiers

PMID: 24086677
DOI: 10.1371/journal.pone.0076001
PMCID: PMC3784423

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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