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Article

Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease.

American journal of human genetics - 1 Jun 2004

van der Walt Joelle M, Noureddine Maher A, Kittappa Raja, Hauser Michael A, Scott William K, McKay Ron, Zhang Fengyu, Stajich Jeffrey M, Fujiwara Kenichiro, Scott Burton L, Pericak-Vance Margaret A, Vance Jeffery M, Martin Eden R

Abstract excerpt

The pathogenic process responsible for the loss of dopaminergic neurons within the substantia nigra of patients with Parkinson disease (PD) is poorly understood. Current research supports the involvement of fibroblast growth factor (FGF20) in the survival of dopaminergic cells. FGF20 is a neurotrophic factor that is preferentially expressed within the substantia nigra of rat brain. The human homologue has been...

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Identifiers

PMID: 15122513
DOI: 10.1086/421052
PMCID: PMC1182076

Genes

FGF20

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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