Genome-wide conditional search for epistatic disease-predisposing variants in human association studies.

Abstract excerpt

Genome-wide search for new disease variants, based on well-established variants, has a long history in linkage analysis but is less well-known in genetic case-control association studies. We developed a simple yet highly efficient conditional search method that can find new variants, which are associated with a disease only through epistatic interaction with another variant and do not necessarily have a direct...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Epistasis, Genetic
• Share to Genetic Predisposition to Disease
• Share to Genome-Wide Association Study