Epistatic module detection for case-control studies: a Bayesian model with a Gibbs sampling strategy.

Abstract excerpt

The detection of epistatic interactive effects of multiple genetic variants on the susceptibility of human complex diseases is a great challenge in genome-wide association studies (GWAS). Although methods have been proposed to identify such interactions, the lack of an explicit definition of epistatic effects, together with computational difficulties, makes the development of new methods indispensable. In this...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bayes Theorem
• Share to Epidemiologic Methods
• Share to Epistasis, Genetic