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Article

Epistatic interactions of genetic loci associated with age-related macular degeneration.

Scientific reports - 23 Jun 2021

Kiel Christina, Nebauer Christoph A, Strunz Tobias, Stelzl Simon, Weber Bernhard H F

Abstract excerpt

The currently largest genome-wide association study (GWAS) for age-related macular degeneration (AMD) defines disease association with genome-wide significance for 52 independent common and rare genetic variants across 34 chromosomal loci. Overall, these loci contain over 7200 variants and are enriched for genes with functions indicating several shared cellular processes. Still, the precise mechanisms leading to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34162900
DOI: 10.1038/s41598-021-92351-4
PMCID: PMC8222216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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