Article
Analysis of intraflagellar transport in C. elegans sensory cilia.
Methods in cell biology - 1 Jan 2009
Hao Limin, Acar Seyda, Evans James, Ou Guangshuo, Scholey Jonathan M
Abstract excerpt
Cilia are assembled and maintained by intraflagellar transport (IFT), the motor-dependent, bidirectional movement of multiprotein complexes, called IFT particles, along the axoneme. The sensory cilia of Caenorhabditis elegans represent very useful objects for studying IFT because of the availability of in vivo time-lapse fluorescence microscopy assays of IFT and multiple ciliary mutants. In this system there are...
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