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Article

Functional differentiation of cooperating kinesin-2 motors orchestrates cargo import and transport in C. elegans cilia.

Nature cell biology - 1 Dec 2015

Prevo Bram, Mangeol Pierre, Oswald Felix, Scholey Jonathan M, Peterman Erwin J G

Abstract excerpt

Intracellular transport depends on cooperation between distinct motor proteins. Two anterograde intraflagellar transport (IFT) motors, heterotrimeric kinesin-II and homodimeric OSM-3, cooperate to move cargo along Caenorhabditis elegans cilia. Here, using quantitative fluorescence microscopy, with single-molecule sensitivity, of IFT in living strains containing single-copy transgenes encoding fluorescent IFT...

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PMID: 26523365
DOI: 10.1038/ncb3263

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OSM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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