Article
Functional coordination of intraflagellar transport motors.
Nature - 28 Jul 2005
Ou Guangshuo, Blacque Oliver E, Snow Joshua J, Leroux Michel R, Scholey Jonathan M
Abstract excerpt
Cilia have diverse roles in motility and sensory reception, and defects in cilia function contribute to ciliary diseases such as Bardet-Biedl syndrome (BBS). Intraflagellar transport (IFT) motors assemble and maintain cilia by transporting ciliary precursors, bound to protein complexes called IFT particles, from the base of the cilium to their site of incorporation at the distal tip. In Caenorhabditis elegans,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
